Sampling and evidence synthesis: how much is enough?

At the heart of evidence synthesis is a fundamental question which seems unresolved and rarely articulated: Of the evidence produced in trials, for a given intervention, how much do you need to produce a fit-for-purpose evidence review? In my more naive years I assumed systematic reviews got all the evidence. Alas, that is clearly not the case. Therefore, if its not all the evidence it’s … Continue reading Sampling and evidence synthesis: how much is enough?

Screening studies for reviews: two papers

Single screening versus conventional double screening for study selection in systematic reviews: a methodological systematic review. Waffenschmidt S BMC Medical Research Methodology 2019;19:132 This concludes: “Single screening of the titles and abstracts of studies retrieved in bibliographic searches is not equivalent to double screening, as substantially more studies are missed. However, in our opinion such an approach could still represent an appropriate methodological shortcut in … Continue reading Screening studies for reviews: two papers

Three new articles:

Article 1: Excluding non-English publications from evidence-syntheses did not change conclusions: a meta-epidemiological study. Nussbaumer-Streit B et al. 2019 Nov 4. Conclusion: Exclusion of non-English publications from systematic reviews on clinical interventions had a minimal effect on overall conclusions and could be a viable methodological shortcut, especially for rapid reviews. Comment: Nice to see (not) that the systematic review world appear to care little for … Continue reading Three new articles: