The Cochrane HPV vaccine review was incomplete and ignored important evidence of bias

The Cochrane HPV vaccine review was incomplete and ignored important evidence of bias by Lars Jørgensen, Peter C Gøtzsche, Tom Jefferson (BMJ Evidence-Based Medicine 2018) This is a highly critical article pointing out that the review missed nearly half of eligible trials.  They also land some heavy punches with comments such as: “Cochrane’s public relations of the review were uncritical“ “In our view, this is not … Continue reading The Cochrane HPV vaccine review was incomplete and ignored important evidence of bias

Value of Information to help with the SR v RR debate?

I posted a post-Evidence Live blog last week which explored the notion of harms associated with doing rapid reviews (RRs). There is overlap from that post but I’ve had time to reflect and hopefully this will be better written. I’ve also added a vote!!  It may need re-writing again, if you think it needs clarification then please let me know! The question I was asked … Continue reading Value of Information to help with the SR v RR debate?

Systematic versus rapid reviews – what about harms?

I was at the wonderful Evidence Live and presented on rapid reviews. One question came from the wonderful Iain Chalmers who asked about the potential for harm if health professionals followed the advice of a RR that was subsequently shown to be wrong. Later, in conversation, it became clear that ‘wrong’ meant a reversal of conclusion – so the SR might say the intervention is … Continue reading Systematic versus rapid reviews – what about harms?

Two new posts (well, new to the site)

Abbreviated literature searches were viable alternatives to comprehensive searches: a meta-epidemiological study. Nussbaumer-Streit B. et al. J Clin Epidemiol. 2018 Jun 1 A paper highlighting that abbreviated searches typically produce very similar results. The authors conclude: “If decision makers are willing to accept less certainty and a small risk for opposite conclusions, some abbreviated searches are viable options for rapid evidence syntheses. Decisions demanding high … Continue reading Two new posts (well, new to the site)

HTAi 2018

I had the pleasure of presenting at the HTAi 2018 conference in Vancouver which ended yesterday. Here is a picture from the event, shared as (a) the unplanned colour co-ordination is impeccable and (b) people have commented I look like a game show host. I talked about, you guessed it, rapid reviews. My emphasis was on the fact that, whatever the review type, you never … Continue reading HTAi 2018

Developing PRISMA-RR, a reporting guideline for rapid reviews of primary studies

Developing PRISMA-RR, a reporting guideline for rapid reviews of primary studies. Stevens A et al.  2018 This is a protocol describing the development of reporting guidelines for rapid reviews (following similar work in systematic reviews. See the PRISMA website). The authors state: “The objective of this project is to create an evidence-based, consensus-derived minimum guidance for uthors writing reports of rapid reviews of primary studies.” The … Continue reading Developing PRISMA-RR, a reporting guideline for rapid reviews of primary studies

Do policy-makers find commissioned rapid reviews useful?

Do policy-makers find commissioned rapid reviews useful? Moore G et al Health Research Policy and Systems 2018 16:17 Abstract Background Rapid reviews are increasingly used by policy agencies to access relevant research in short timeframes. Despite the growing number of programmes, little is known about how rapid reviews are used by health policy agencies. This study examined whether and how rapid reviews commissioned using a … Continue reading Do policy-makers find commissioned rapid reviews useful?

Two oral conference submissions from Uni of Sheffield

I came across two papers that have been submitted to a conference – but I’ve no idea which conference!  The first author is the same – Katy Cooper: The first is Selecting Rapid Review Methods For Health Technology Assessment which concludes: “Rapid review methods need to be chosen to fit the needs of the review, each of which may have different challenges. Collaboration between those producing rapid … Continue reading Two oral conference submissions from Uni of Sheffield